The USMLE Step 1 exam tests the Basic Sciences. Designed for US Medical Student’s in their second year of Medical School, before their Clinical Rotations, International Medical Graduates will often struggle with going back to basics, and thinking like a pre-clinical student, rather than a qualified Physician. Try these USMLE Step 1 Anatomy questions and find out what you face on exam day!
Directions: Look at the sample USMLE questions below and explore the sorts of questions you’ll face on the exam. The USMLE Step 1 exam questions are in Clinical Vignette format, meaning that you will be asked to pull on information from a number of different disciplines and organ systems and that you will be required to make a number of conclusions based on the limited information provided.
This means if you do not have enough knowledge to make numerous conclusions on a topic then you’re likely to get the question wrong.
You will see below a number of USMLE questions with multiple choice answers. There is one best answer and no negative marking on the USMLE exam, so we recommend you guess if you are unsure or running out of test time.
Click on the get answer button to download the answers and explanations.
Question
A mother brings her 4-year-old child into the hospital complaining that the child has been extremely lethargic over the past few days. Blood tests reveal that the boy’s hematocrit is below normal levels, but no Heiny bodies are present in his RBCs. In questioning the mother about the child’s behaviour and eating habits, it is revealed that the child eats a reasonably well balanced diet, but often places non-food objects in his mouth and eats them. It is also noted that the mother is single and lives in a substandard 60-year-old housing development. What is the most likely explanation for the child’s anemia?
A. Glucose 6-phosphate dehydrogenase (G-6-PD) deficiency
B. Inadequate iron in the diet
C. Inhibition of heme oxygenase activity
D. Inhibition of ALA dehydratase activity
E. Inhibition of ALA synthase activity
