The USMLE Step 1 exam tests the Basic Sciences. Designed for US Medical Student’s in their second year of Medical School, before their Clinical Rotations, International Medical Graduates will often struggle with going back to basics, and thinking like a pre-clinical student, rather than a qualified Physician. Try these USMLE Step 1 Anatomy questions and find out what you face on exam day!
Directions: Look at the sample USMLE questions below and explore the sorts of questions you’ll face on the exam. The USMLE Step 1 exam questions are in Clinical Vignette format, meaning that you will be asked to pull on information from a number of different disciplines and organ systems and that you will be required to make a number of conclusions based on the limited information provided.
This means if you do not have enough knowledge to make numerous conclusions on a topic then you’re likely to get the question wrong.
You will see below a number of USMLE questions with multiple choice answers. There is one best answer and no negative marking on the USMLE exam, so we recommend you guess if you are unsure or running out of test time.
Click on the get answer button to download the answers and explanations.
Question:
A 35-year-old woman presents with lymphadenopathy in the supraclavicular node. She noticed the lump several months ago but initially ignored it because it did not hurt. She subjectively reports fever. Excisional biopsy of the node reveals a 2-cm node with a mixed cellular infiltrate of lymphocytes, eosinophils, and lacunar cells. Reed-Sternberg cells are also present. Which of the following is the most likely diagnosis?
A. Hodgkin lymphoma
B. Non-Hodgkin lymphoma
C. Polycythemia vera
D. Reactive lymphadenopathy
E. Thoracic outlet syndrome
